Farmaci Antiretrovirali

I farmaci che vengono impiegati nella HAART si possono classificare in:

• Inibitori nucleosidici/nucleotidici della Trascrittasi inversa (Emtricitabina-FTC, Lamivudina-3TC, Zidovudina-AZT, Abacavir-ABC, Tenofovir disoproxil fumarato-TDF, Tenofovir alafenamide fumarato-TAF);
• Inibitori non nucleosidici della Trascrittasi inversa (Efavirenz-EFV, Nevirapina-NVP, Etravirina-ETR, Doravirina-DOR, Rilpivirina-RPV);
• Inibitori della Proteasi (Lopinavir/ritonavir-LPV/r, Ritonavir-RTV, Darunavir-DRV, Atazanavir-ATV)
• Inibitori della Fusione ed Ingresso (Enfuvirtide-ENF T20, Maraviroc-MVC);
• Inibitori dell’Integrasi (Raltegravir-RAL, Elvitegravir-EVG, Dolutegravir-DTG, Bictegravir-BIC, Cabotegravir).

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SINGLE-TABLET REGIMENS

• ATRIPLA cpr 600mg/200mg/245mg (EFV/FTC/TDF)
• BIKTARVY cpr 50mg/200mg/25mg (BIC/FTC/TAF)
• DELSTRIGO cpr 100mg/300mg/245mg (DOR/3TC/TDF)
• DOVATO cpr 50mg/300mg (DTG/3TC)
• EVIPLERA cpr 200mg/25mg/245mg (FTC/RPV/TDF)
• GENVOYA cpr 150mg/150mg/200 mg/10 mg (EVG/c/FTC/TAF)
• JULUCA cpr 50mg/25mg (DTG/RPV)
• ODEFSEY cpr 200mg/25mg/25mg (FTC/RPV/TAF)
• STRIBILD cpr 150mg/150mg/200mg/245mg (EVG/c/FTC/TDF)
• SYMTUZA cpr 800mg/150mg/200mg/10mg (DRV/c/FTC/TAF)
• TRIUMEQ cpr 50mg/600mg/300mg (DTG/ABC/3TC)

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TERAPIE COMBINATE DI INIBITORI NUCLEOSI(TI)DICI DELLA TRASCRITTASI INVERSA

• CIMDUO cpr 300mg/300mg (TDF/3TC) – Non disponibile in Italia
• COMBIVIR cpr 150mg/300mg (3TC/AZT)
• DESCOVY cpr 200mg/10mg (TAF/FTC)
• KIVEXA cpr 600mg/300mg (ABC/3TC)
• TRIZIVIR cpr 300mg/150mg/300mg (ABC/3TC/AZT)
• TRUVADA cpr 200mg/245mg (FTC/TDF)

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BOOSTER

• NORVIR 100mg (Ritonavir-RTV)
• TYBOST 150mg (Cobicistat-COBI)

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SINGOLI INIBITORI NUCLEOSI(TI)DICI DELLA TRASCRITTASI INVERSA

• EMTRIVA cps 200mg (FTC)
• EPIVIR cpr 150mg, cpr 300mg (3TC)
• RETROVIR (AZT)
• VIREAD cpr 123mg (TDF)
• ZIAGEN cpr 300mg (ABC)

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SINGOLI INIBITORI NON NUCLEOSIDICI DELLA TRASCRITTASI INVERSA

• EDURANT cpr 25mg (RPV)
• INTELENCE cpr 25mg, cpr 100mg, cpr 200mg (ETR)
• PIFELTRO cpr 100mg (DOR)
• SUSTIVA cps 50mg, cps 100mg, cps 200mg (EFV)
• VIRAMUNE cpr 200mg (NVP)

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SINGOLI INIBITORI DELLE PROTEASI

• PREZISTA cpr 400mg, cpr 600mg, cpr 800mg, sospensione 100mg/ml (DRV)
• REYATAZ cps 100mg, cps 150mg, cps 200mg, cps 300mg (ATV)

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INIBITORI DELLE PROTEASI boosterati

• EVOTAZ cpr 300mg/150mg (ATV/c)
• REZOLSTA cpr 800mg/150mg (DRV/c)
• KALETRA cpr 100mg/25mg, cpr 200mg/50mg, sospensione orale 80mg+20mg/ml (LPV/r)

 

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INIBITORI DELL’INTEGRASI

• ISENTRESS cpr 400mg, cpr 600mg (RAL)
• TIVICAY cpr 10mg, cpr 25mg, cpr 50mg (DTG)

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INIBITORI DELLA FUSIONE/INGRESSO

• FUSEON fl sc 90mg/ml (ENF)
• CELSENTRI cpr 25mg, cpr 75mg, cpr 150mg, cpr 300mg (MVC)